Is this the same as stem-cell treatment?
No. Supernatant uses substances released during cell culture; it is not the administration of living stem cells.
REGENERATIVE MEDICINE
Culture supernatant & exosomes
Understand the product and evidence
Supernatant contains substances released during cell culture; exosomes are small cell-released vesicles. These are not synonyms or living stem-cell treatment. The official page describes a concentrated culture supernatant containing growth factors such as EGF, IGF, TGF-β, PDGF, HGF, VEGF and KGF.
How it works
The clinic lists infusions and skin-booster injections. Confirm source, manufacturing, quality tests, dose and route for the actual preparation.
Visits & recovery
Schedules depend on the product and purpose. Do not interpret it as guaranteed rejuvenation, cure or prevention; discuss alternatives and costs.
Risks & considerations
Discuss pain, swelling, bruising, allergy and infection. A July 2024 MHLW notice reported no approved medicines of this kind and highlighted safety concerns and uncertainty. The official page notes the products are cultured in serum-free media and have undergone safety tests including intradermal reaction, toxicity and antigenicity.
Fees at a glance
Selected published fees, in Japanese yen including tax—not a complete price range or total quote. Elective self-pay care is not covered by Japanese public insurance. Confirm eligibility, session count and consultation, anaesthesia, test and medicine charges.
| Item & conditions | Fee, tax included |
|---|---|
| Culture supernatant / exosome infusion | ¥66,000 |
| Exosome skin-booster injection / standard | ¥88,000 |
The published stem-cell administration fees include tests, fat collection and culture. Repeat treatment and patients without Japanese public health insurance have different prices. Interpreting requires advance booking and an extra fee. Supernatant/exosome efficacy and safety remain uncertain.
All clinic fees & conditions (Japanese) (opens in a new tab)Common questions
Is safety established?
A July 2024 MHLW notice reported no approved medicines of this kind and highlighted safety concerns and uncertainty; informed consent is essential.
Book online (opens in a new tab)Culture supernatant & exosomes: Full clinic guide (Japanese) (opens in a new tab)
← Regenerative medicine